AustralieFrV1, Main, Exploration, bibRecord, 004189

Effects of timing, location and definition of reinfarction on mortality in patients with totally occluded infarct related arteries late after myocardial infarction

Identifieur interne : 004189 ( Main/Exploration ); précédent : 004188; suivant : 004190

Effects of timing, location and definition of reinfarction on mortality in patients with totally occluded infarct related arteries late after myocardial infarction

Auteurs : Christopher Adlbrecht [Autriche] ; Kurt Huber [Autriche] ; Harmony R. Reynolds [États-Unis] ; Antonio C. Carvalho [Brésil] ; Vladimír Dzavik [Canada] ; Philippe Gabriel Steg [France] ; LI LIU [États-Unis] ; Paolo Marino [Italie] ; Camille A. Pearte [États-Unis] ; James M. Rankin [Australie] ; Harvey D. White [Nouvelle-Zélande] ; Gervasio A. Lamasl [Nouvelle-Zélande] ; Judith S. Hochman [États-Unis]

Source :

International journal of cardiology [ 0167-5273 ] ; 2014.

RBID : Pascal:14-0140493

Descripteurs français

KwdFr :
- Adulte d'âge moyen, Facteurs temps, Femelle, Humains, Infarctus du myocarde (), Infarctus du myocarde (anatomopathologie), Infarctus du myocarde (mortalité), Mâle, Occlusion coronarienne (), Occlusion coronarienne (anatomopathologie), Récidive, Études de suivi.
MESH :
- anatomopathologie : Infarctus du myocarde, Occlusion coronarienne.
- mortalité : Infarctus du myocarde.
Pascal (Inist)
- Adulte d'âge moyen, Facteurs temps, Femelle, Humains, Infarctus du myocarde, Mâle, Occlusion coronarienne, Pathologie de l'appareil circulatoire, Récidive, Timing, Etude temporelle, Définition, Mortalité, Pronostic, Epidémiologie, Homme, Malade, Artère, Tardif, Revascularisation, Cardiologie, Études de suivi.
Wicri :
- topic : Mortalité, Homme.

English descriptors

KwdEn :
- Artery, Cardiology, Cardiovascular disease, Coronary Occlusion (complications), Coronary Occlusion (pathology), Coronary Occlusion (therapy), Definition, Epidemiology, Female, Follow-Up Studies, Human, Humans, Late, Male, Middle Aged, Mortality, Myocardial Infarction (complications), Myocardial Infarction (mortality), Myocardial Infarction (pathology), Myocardial Infarction (therapy), Myocardial infarction, Patient, Prognosis, Recurrence, Revascularization, Temporal study, Time Factors, Timing.
MESH :
- complications : Coronary Occlusion, Myocardial Infarction.
- mortality : Myocardial Infarction.
- pathology : Coronary Occlusion, Myocardial Infarction.
- therapy : Coronary Occlusion, Myocardial Infarction.
- Female, Follow-Up Studies, Humans, Male, Middle Aged, Recurrence, Time Factors.

Abstract

Background: The Occluded Artery Trial (OAT) randomized stable patients (n = 2201) >24 h (calendar days 3-28) after myocardial infarction (MI) with totally occluded infarct-related arteries (IRA), to percutaneous coronary intervention (PCI) with optimal medical therapy, or optimal medical therapy alone (MED). PCI had no impact on the composite of death, reinfarction, or class IV heart failure over extended follow-up of up to 9 years. We evaluated the impact of early and late reinfarction and definition of MI on subsequent mortality. Methods and results: Reinfarction was adjudicated according to an adaptation of the 2007 universal definition of MI and the OAT definition (≥2 of the following - symptoms, EKG and biomarkers). Cox regression models were used to analyze the effect of post-randomization reinfarction and baseline variables on time to death. After adjustment for baseline characteristics the 169 (PCI: n = 95; MED: n = 74) patients who developed reinfarction by the universal definition had a 4.15-fold (95% CI 3.03-5.69, p < 0.001) increased risk of death compared to patients without reinfarction. This risk was similar for both treatment groups (interaction p = 0.26) and when MI was defined by the stricter OAT criteria. Reinfarctions occurring within 6 months of randomization had similar impact on mortality as reinfarctions occurring later, and the impact of reinfarction due to the same IRA and a different epicardial vessel was similar. Conclusions: For stable post-MI patients with totally occluded infarct arteries, reinfarction significantly independently increased the risk of death regardless of the initial management strategy (PCI vs. MED), reinfarction definition, location and early or late occurrence.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067126

Affiliations:

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Effects of timing, location and definition of reinfarction on mortality in patients with totally occluded infarct related arteries late after myocardial infarction</title>
<author><name sortKey="Adlbrecht, Christopher" sort="Adlbrecht, Christopher" uniqKey="Adlbrecht C" first="Christopher" last="Adlbrecht">Christopher Adlbrecht</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Medicine II, Division of Cardiology, Medical University of Vienna</s1>
<s2>Vienna</s2>
<s3>AUT</s3>
<sZ>1 aut.</sZ>
</inist:fA14>
<country>Autriche</country>
<placeName><settlement type="city">Vienne (Autriche)</settlement>
<region nuts="2" type="province">Vienne (Autriche)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Huber, Kurt" sort="Huber, Kurt" uniqKey="Huber K" first="Kurt" last="Huber">Kurt Huber</name>
<affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Department of Internal Medicine, Cardiology and Emergency Medicine, Wilhelminen Hospital</s1>
<s2>Vienna</s2>
<s3>AUT</s3>
<sZ>2 aut.</sZ>
</inist:fA14>
<country>Autriche</country>
<placeName><settlement type="city">Vienne (Autriche)</settlement>
<region nuts="2" type="province">Vienne (Autriche)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Reynolds, Harmony R" sort="Reynolds, Harmony R" uniqKey="Reynolds H" first="Harmony R." last="Reynolds">Harmony R. Reynolds</name>
<affiliation wicri:level="2"><inist:fA14 i1="03"><s1>Cardiovascular Clinical Research Center, New York University School of Medicine</s1>
<s2>New York</s2>
<s3>USA</s3>
<sZ>3 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Carvalho, Antonio C" sort="Carvalho, Antonio C" uniqKey="Carvalho A" first="Antonio C." last="Carvalho">Antonio C. Carvalho</name>
<affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Hospital Sao Paulo</s1>
<s2>Moema, Sao Paulo</s2>
<s3>BRA</s3>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Brésil</country>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Dzavik, Vladimir" sort="Dzavik, Vladimir" uniqKey="Dzavik V" first="Vladimír" last="Dzavik">Vladimír Dzavik</name>
<affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Peter Munk Cardiac Centre, University Health Network</s1>
<s2>Toronto</s2>
<s3>CAN</s3>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>Toronto</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Steg, Philippe Gabriel" sort="Steg, Philippe Gabriel" uniqKey="Steg P" first="Philippe Gabriel" last="Steg">Philippe Gabriel Steg</name>
<affiliation wicri:level="3"><inist:fA14 i1="06"><s1>INSERM U-698</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><inist:fA14 i1="07"><s1>Université Paris-Diderot</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><inist:fA14 i1="08"><s1>Assistance Publique-Hôpitaux de Paris, Centre Hospitalier Bichat-Claude Bernard</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Li Liu" sort="Li Liu" uniqKey="Li Liu" last="Li Liu">LI LIU</name>
<affiliation wicri:level="3"><inist:fA14 i1="09"><s1>Clinical Trial and Surveys Corp.</s1>
<s2>Baltimore</s2>
<s3>USA</s3>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><settlement type="city">Baltimore</settlement>
<region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Marino, Paolo" sort="Marino, Paolo" uniqKey="Marino P" first="Paolo" last="Marino">Paolo Marino</name>
<affiliation wicri:level="1"><inist:fA14 i1="10"><s1>University of Verona/Instituti Ospedalieri</s1>
<s2>Verona</s2>
<s3>ITA</s3>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Italie</country>
<wicri:noRegion>University of Verona/Instituti Ospedalieri</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Pearte, Camille A" sort="Pearte, Camille A" uniqKey="Pearte C" first="Camille A." last="Pearte">Camille A. Pearte</name>
<affiliation wicri:level="2"><inist:fA14 i1="03"><s1>Cardiovascular Clinical Research Center, New York University School of Medicine</s1>
<s2>New York</s2>
<s3>USA</s3>
<sZ>3 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Rankin, James M" sort="Rankin, James M" uniqKey="Rankin J" first="James M." last="Rankin">James M. Rankin</name>
<affiliation wicri:level="1"><inist:fA14 i1="11"><s1>Perth Cardiovascular Institute</s1>
<s2>Perth</s2>
<s3>AUS</s3>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<wicri:noRegion>Perth Cardiovascular Institute</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="White, Harvey D" sort="White, Harvey D" uniqKey="White H" first="Harvey D." last="White">Harvey D. White</name>
<affiliation wicri:level="1"><inist:fA14 i1="12"><s1>Green Lane Cardiovascular Service</s1>
<s2>Auckland</s2>
<s3>NZL</s3>
<sZ>11 aut.</sZ>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>Nouvelle-Zélande</country>
<wicri:noRegion>Green Lane Cardiovascular Service</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lamasl, Gervasio A" sort="Lamasl, Gervasio A" uniqKey="Lamasl G" first="Gervasio A." last="Lamasl">Gervasio A. Lamasl</name>
<affiliation wicri:level="1"><inist:fA14 i1="12"><s1>Green Lane Cardiovascular Service</s1>
<s2>Auckland</s2>
<s3>NZL</s3>
<sZ>11 aut.</sZ>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>Nouvelle-Zélande</country>
<wicri:noRegion>Green Lane Cardiovascular Service</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hochman, Judith S" sort="Hochman, Judith S" uniqKey="Hochman J" first="Judith S." last="Hochman">Judith S. Hochman</name>
<affiliation wicri:level="2"><inist:fA14 i1="03"><s1>Cardiovascular Clinical Research Center, New York University School of Medicine</s1>
<s2>New York</s2>
<s3>USA</s3>
<sZ>3 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">14-0140493</idno>
<date when="2014">2014</date>
<idno type="stanalyst">PASCAL 14-0140493 INIST</idno>
<idno type="RBID">Pascal:14-0140493</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000411</idno>
<idno type="wicri:Area/PascalFrancis/Curation">005A51</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">000334</idno>
<idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000334</idno>
<idno type="wicri:doubleKey">0167-5273:2014:Adlbrecht C:effects:of:timing</idno>
<idno type="wicri:Area/Main/Merge">004258</idno>
<idno type="wicri:source">PMC</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067126</idno>
<idno type="RBID">PMC:4067126</idno>
<idno type="wicri:Area/Pmc/Corpus">002013</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002013</idno>
<idno type="wicri:Area/Pmc/Curation">001E67</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001E67</idno>
<idno type="wicri:Area/Pmc/Checkpoint">001620</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001620</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="wicri:Area/PubMed/Corpus">003709</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">003709</idno>
<idno type="wicri:Area/PubMed/Curation">003595</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">003595</idno>
<idno type="wicri:Area/PubMed/Checkpoint">003595</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">003595</idno>
<idno type="wicri:Area/Ncbi/Merge">001956</idno>
<idno type="wicri:Area/Ncbi/Curation">001956</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">001956</idno>
<idno type="wicri:doubleKey">0167-5273:2014:Adlbrecht C:effects:of:timing</idno>
<idno type="wicri:Area/Main/Merge">003A37</idno>
<idno type="wicri:Area/Main/Curation">004189</idno>
<idno type="wicri:Area/Main/Exploration">004189</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Effects of timing, location and definition of reinfarction on mortality in patients with totally occluded infarct related arteries late after myocardial infarction</title>
<author><name sortKey="Adlbrecht, Christopher" sort="Adlbrecht, Christopher" uniqKey="Adlbrecht C" first="Christopher" last="Adlbrecht">Christopher Adlbrecht</name>
<affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Medicine II, Division of Cardiology, Medical University of Vienna</s1>
<s2>Vienna</s2>
<s3>AUT</s3>
<sZ>1 aut.</sZ>
</inist:fA14>
<country>Autriche</country>
<placeName><settlement type="city">Vienne (Autriche)</settlement>
<region nuts="2" type="province">Vienne (Autriche)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Huber, Kurt" sort="Huber, Kurt" uniqKey="Huber K" first="Kurt" last="Huber">Kurt Huber</name>
<affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Department of Internal Medicine, Cardiology and Emergency Medicine, Wilhelminen Hospital</s1>
<s2>Vienna</s2>
<s3>AUT</s3>
<sZ>2 aut.</sZ>
</inist:fA14>
<country>Autriche</country>
<placeName><settlement type="city">Vienne (Autriche)</settlement>
<region nuts="2" type="province">Vienne (Autriche)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Reynolds, Harmony R" sort="Reynolds, Harmony R" uniqKey="Reynolds H" first="Harmony R." last="Reynolds">Harmony R. Reynolds</name>
<affiliation wicri:level="2"><inist:fA14 i1="03"><s1>Cardiovascular Clinical Research Center, New York University School of Medicine</s1>
<s2>New York</s2>
<s3>USA</s3>
<sZ>3 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Carvalho, Antonio C" sort="Carvalho, Antonio C" uniqKey="Carvalho A" first="Antonio C." last="Carvalho">Antonio C. Carvalho</name>
<affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Hospital Sao Paulo</s1>
<s2>Moema, Sao Paulo</s2>
<s3>BRA</s3>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Brésil</country>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Dzavik, Vladimir" sort="Dzavik, Vladimir" uniqKey="Dzavik V" first="Vladimír" last="Dzavik">Vladimír Dzavik</name>
<affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Peter Munk Cardiac Centre, University Health Network</s1>
<s2>Toronto</s2>
<s3>CAN</s3>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>Toronto</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Steg, Philippe Gabriel" sort="Steg, Philippe Gabriel" uniqKey="Steg P" first="Philippe Gabriel" last="Steg">Philippe Gabriel Steg</name>
<affiliation wicri:level="3"><inist:fA14 i1="06"><s1>INSERM U-698</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><inist:fA14 i1="07"><s1>Université Paris-Diderot</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><inist:fA14 i1="08"><s1>Assistance Publique-Hôpitaux de Paris, Centre Hospitalier Bichat-Claude Bernard</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Li Liu" sort="Li Liu" uniqKey="Li Liu" last="Li Liu">LI LIU</name>
<affiliation wicri:level="3"><inist:fA14 i1="09"><s1>Clinical Trial and Surveys Corp.</s1>
<s2>Baltimore</s2>
<s3>USA</s3>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><settlement type="city">Baltimore</settlement>
<region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Marino, Paolo" sort="Marino, Paolo" uniqKey="Marino P" first="Paolo" last="Marino">Paolo Marino</name>
<affiliation wicri:level="1"><inist:fA14 i1="10"><s1>University of Verona/Instituti Ospedalieri</s1>
<s2>Verona</s2>
<s3>ITA</s3>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Italie</country>
<wicri:noRegion>University of Verona/Instituti Ospedalieri</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Pearte, Camille A" sort="Pearte, Camille A" uniqKey="Pearte C" first="Camille A." last="Pearte">Camille A. Pearte</name>
<affiliation wicri:level="2"><inist:fA14 i1="03"><s1>Cardiovascular Clinical Research Center, New York University School of Medicine</s1>
<s2>New York</s2>
<s3>USA</s3>
<sZ>3 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Rankin, James M" sort="Rankin, James M" uniqKey="Rankin J" first="James M." last="Rankin">James M. Rankin</name>
<affiliation wicri:level="1"><inist:fA14 i1="11"><s1>Perth Cardiovascular Institute</s1>
<s2>Perth</s2>
<s3>AUS</s3>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<wicri:noRegion>Perth Cardiovascular Institute</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="White, Harvey D" sort="White, Harvey D" uniqKey="White H" first="Harvey D." last="White">Harvey D. White</name>
<affiliation wicri:level="1"><inist:fA14 i1="12"><s1>Green Lane Cardiovascular Service</s1>
<s2>Auckland</s2>
<s3>NZL</s3>
<sZ>11 aut.</sZ>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>Nouvelle-Zélande</country>
<wicri:noRegion>Green Lane Cardiovascular Service</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lamasl, Gervasio A" sort="Lamasl, Gervasio A" uniqKey="Lamasl G" first="Gervasio A." last="Lamasl">Gervasio A. Lamasl</name>
<affiliation wicri:level="1"><inist:fA14 i1="12"><s1>Green Lane Cardiovascular Service</s1>
<s2>Auckland</s2>
<s3>NZL</s3>
<sZ>11 aut.</sZ>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>Nouvelle-Zélande</country>
<wicri:noRegion>Green Lane Cardiovascular Service</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hochman, Judith S" sort="Hochman, Judith S" uniqKey="Hochman J" first="Judith S." last="Hochman">Judith S. Hochman</name>
<affiliation wicri:level="2"><inist:fA14 i1="03"><s1>Cardiovascular Clinical Research Center, New York University School of Medicine</s1>
<s2>New York</s2>
<s3>USA</s3>
<sZ>3 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">International journal of cardiology</title>
<title level="j" type="abbreviated">Int. j. cardiol.</title>
<idno type="ISSN">0167-5273</idno>
<imprint><date when="2014">2014</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">International journal of cardiology</title>
<title level="j" type="abbreviated">Int. j. cardiol.</title>
<idno type="ISSN">0167-5273</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Artery</term>
<term>Cardiology</term>
<term>Cardiovascular disease</term>
<term>Coronary Occlusion (complications)</term>
<term>Coronary Occlusion (pathology)</term>
<term>Coronary Occlusion (therapy)</term>
<term>Definition</term>
<term>Epidemiology</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Human</term>
<term>Humans</term>
<term>Late</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Mortality</term>
<term>Myocardial Infarction (complications)</term>
<term>Myocardial Infarction (mortality)</term>
<term>Myocardial Infarction (pathology)</term>
<term>Myocardial Infarction (therapy)</term>
<term>Myocardial infarction</term>
<term>Patient</term>
<term>Prognosis</term>
<term>Recurrence</term>
<term>Revascularization</term>
<term>Temporal study</term>
<term>Time Factors</term>
<term>Timing</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Facteurs temps</term>
<term>Femelle</term>
<term>Humains</term>
<term>Infarctus du myocarde ()</term>
<term>Infarctus du myocarde (anatomopathologie)</term>
<term>Infarctus du myocarde (mortalité)</term>
<term>Mâle</term>
<term>Occlusion coronarienne ()</term>
<term>Occlusion coronarienne (anatomopathologie)</term>
<term>Récidive</term>
<term>Études de suivi</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Infarctus du myocarde</term>
<term>Occlusion coronarienne</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Coronary Occlusion</term>
<term>Myocardial Infarction</term>
</keywords>
<keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Myocardial Infarction</term>
</keywords>
<keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Infarctus du myocarde</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Coronary Occlusion</term>
<term>Myocardial Infarction</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Coronary Occlusion</term>
<term>Myocardial Infarction</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Recurrence</term>
<term>Time Factors</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Facteurs temps</term>
<term>Femelle</term>
<term>Humains</term>
<term>Infarctus du myocarde</term>
<term>Mâle</term>
<term>Occlusion coronarienne</term>
<term>Pathologie de l'appareil circulatoire</term>
<term>Récidive</term>
<term>Timing</term>
<term>Etude temporelle</term>
<term>Définition</term>
<term>Mortalité</term>
<term>Pronostic</term>
<term>Epidémiologie</term>
<term>Homme</term>
<term>Malade</term>
<term>Artère</term>
<term>Tardif</term>
<term>Revascularisation</term>
<term>Cardiologie</term>
<term>Études de suivi</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Mortalité</term>
<term>Homme</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Background: The Occluded Artery Trial (OAT) randomized stable patients (n = 2201) >24 h (calendar days 3-28) after myocardial infarction (MI) with totally occluded infarct-related arteries (IRA), to percutaneous coronary intervention (PCI) with optimal medical therapy, or optimal medical therapy alone (MED). PCI had no impact on the composite of death, reinfarction, or class IV heart failure over extended follow-up of up to 9 years. We evaluated the impact of early and late reinfarction and definition of MI on subsequent mortality. Methods and results: Reinfarction was adjudicated according to an adaptation of the 2007 universal definition of MI and the OAT definition (≥2 of the following - symptoms, EKG and biomarkers). Cox regression models were used to analyze the effect of post-randomization reinfarction and baseline variables on time to death. After adjustment for baseline characteristics the 169 (PCI: n = 95; MED: n = 74) patients who developed reinfarction by the universal definition had a 4.15-fold (95% CI 3.03-5.69, p < 0.001) increased risk of death compared to patients without reinfarction. This risk was similar for both treatment groups (interaction p = 0.26) and when MI was defined by the stricter OAT criteria. Reinfarctions occurring within 6 months of randomization had similar impact on mortality as reinfarctions occurring later, and the impact of reinfarction due to the same IRA and a different epicardial vessel was similar. Conclusions: For stable post-MI patients with totally occluded infarct arteries, reinfarction significantly independently increased the risk of death regardless of the initial management strategy (PCI vs. MED), reinfarction definition, location and early or late occurrence.</div>
</front>
</TEI>
<affiliations><list><country><li>Australie</li>
<li>Autriche</li>
<li>Brésil</li>
<li>Canada</li>
<li>France</li>
<li>Italie</li>
<li>Nouvelle-Zélande</li>
<li>États-Unis</li>
</country>
<region><li>Maryland</li>
<li>Vienne (Autriche)</li>
<li>État de New York</li>
<li>État de São Paulo</li>
<li>Île-de-France</li>
</region>
<settlement><li>Baltimore</li>
<li>Paris</li>
<li>São Paulo</li>
<li>Vienne (Autriche)</li>
</settlement>
</list>
<tree><country name="Autriche"><region name="Vienne (Autriche)"><name sortKey="Adlbrecht, Christopher" sort="Adlbrecht, Christopher" uniqKey="Adlbrecht C" first="Christopher" last="Adlbrecht">Christopher Adlbrecht</name>
</region>
<name sortKey="Huber, Kurt" sort="Huber, Kurt" uniqKey="Huber K" first="Kurt" last="Huber">Kurt Huber</name>
</country>
<country name="États-Unis"><region name="État de New York"><name sortKey="Reynolds, Harmony R" sort="Reynolds, Harmony R" uniqKey="Reynolds H" first="Harmony R." last="Reynolds">Harmony R. Reynolds</name>
</region>
<name sortKey="Hochman, Judith S" sort="Hochman, Judith S" uniqKey="Hochman J" first="Judith S." last="Hochman">Judith S. Hochman</name>
<name sortKey="Li Liu" sort="Li Liu" uniqKey="Li Liu" last="Li Liu">LI LIU</name>
<name sortKey="Pearte, Camille A" sort="Pearte, Camille A" uniqKey="Pearte C" first="Camille A." last="Pearte">Camille A. Pearte</name>
</country>
<country name="Brésil"><region name="État de São Paulo"><name sortKey="Carvalho, Antonio C" sort="Carvalho, Antonio C" uniqKey="Carvalho A" first="Antonio C." last="Carvalho">Antonio C. Carvalho</name>
</region>
</country>
<country name="Canada"><noRegion><name sortKey="Dzavik, Vladimir" sort="Dzavik, Vladimir" uniqKey="Dzavik V" first="Vladimír" last="Dzavik">Vladimír Dzavik</name>
</noRegion>
</country>
<country name="France"><region name="Île-de-France"><name sortKey="Steg, Philippe Gabriel" sort="Steg, Philippe Gabriel" uniqKey="Steg P" first="Philippe Gabriel" last="Steg">Philippe Gabriel Steg</name>
</region>
<name sortKey="Steg, Philippe Gabriel" sort="Steg, Philippe Gabriel" uniqKey="Steg P" first="Philippe Gabriel" last="Steg">Philippe Gabriel Steg</name>
<name sortKey="Steg, Philippe Gabriel" sort="Steg, Philippe Gabriel" uniqKey="Steg P" first="Philippe Gabriel" last="Steg">Philippe Gabriel Steg</name>
</country>
<country name="Italie"><noRegion><name sortKey="Marino, Paolo" sort="Marino, Paolo" uniqKey="Marino P" first="Paolo" last="Marino">Paolo Marino</name>
</noRegion>
</country>
<country name="Australie"><noRegion><name sortKey="Rankin, James M" sort="Rankin, James M" uniqKey="Rankin J" first="James M." last="Rankin">James M. Rankin</name>
</noRegion>
</country>
<country name="Nouvelle-Zélande"><noRegion><name sortKey="White, Harvey D" sort="White, Harvey D" uniqKey="White H" first="Harvey D." last="White">Harvey D. White</name>
</noRegion>
<name sortKey="Lamasl, Gervasio A" sort="Lamasl, Gervasio A" uniqKey="Lamasl G" first="Gervasio A." last="Lamasl">Gervasio A. Lamasl</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004189 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 004189 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Asie
   |area=    AustralieFrV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     Pascal:14-0140493
   |texte=   Effects of timing, location and definition of reinfarction on mortality in patients with totally occluded infarct related arteries late after myocardial infarction
}}

This area was generated with Dilib version V0.6.33.
Data generation: Tue Dec 5 10:43:12 2017. Site generation: Tue Mar 5 14:07:20 2024

Serveur d'exploration sur les relations entre la France et l'Australie

Effects of timing, location and definition of reinfarction on mortality in patients with totally occluded infarct related arteries late after myocardial infarction

Effects of timing, location and definition of reinfarction on mortality in patients with totally occluded infarct related arteries late after myocardial infarction

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Serveur d'exploration sur les relations entre la France et l'Australie
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.